IRRESTRAINABLE
\ɪɹɪstɹˈe͡ɪnəbə͡l], \ɪɹɪstɹˈeɪnəbəl], \ɪ_ɹ_ɪ_s_t_ɹ_ˈeɪ_n_ə_b_əl]\
Definitions of IRRESTRAINABLE
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ir-re-str[=a]n'a-bl, adj. not restrainable.
By Thomas Davidson
Word of the day
ATP Binding Cassette, Sub Family B Proteins
- A subfamily transmembrane the superfamily TRANSPORTERS that closely related in GLYCOPROTEIN. When overexpressed, function as dependent efflux pumps able extrude lipophilic drugs, especially ANTINEOPLASTIC AGENTS, from cells causing resistance (DRUG RESISTANCE, MULTIPLE). Although P-Glycoproteins share functional similarities to MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS they are two distinct subclasses of ATP-BINDING CASSETTE TRANSPORTERS, and have little sequence homology.