INSULIN RECEPTOR BETA SUBUNIT
\ˈɪnsuːlˌɪn ɹɪsˈɛptə bˈiːtə sˈʌbjuːnˌɪt], \ˈɪnsuːlˌɪn ɹɪsˈɛptə bˈiːtə sˈʌbjuːnˌɪt], \ˈɪ_n_s_uː_l_ˌɪ_n ɹ_ɪ_s_ˈɛ_p_t_ə b_ˈiː_t_ə s_ˈʌ_b_j_uː_n_ˌɪ_t]\
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A cell surface receptor for INSULIN. It is comprised of a tetramer of two alpha and two beta subunits which are derived from cleavage of a single precusor protein. The receptor contains an intrinsic tyrosine kinase domain that is located within the beta subunit. Activation of the receptor by INSULIN results in numerous metabolic changes including increased uptake of GLUCOSE into the LIVER; MUSCLE; and ADIPOSE TISSUE. EC 2.7.11.-.
By DataStellar Co., Ltd
