INOSCLEROMA
\ɪnˌɒskləɹˈə͡ʊmə], \ɪnˌɒskləɹˈəʊmə], \ɪ_n_ˌɒ_s_k_l_ə_ɹ_ˈəʊ_m_ə]\
Definitions of INOSCLEROMA
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By Robley Dunglison
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.