INCISAL ANGLE

\ɪnsˈɪsə͡l ˈaŋɡə͡l], \ɪnsˈɪsə‍l ˈaŋɡə‍l], \ɪ_n_s_ˈɪ_s_əl ˈa_ŋ_ɡ_əl]\

Definitions of INCISAL ANGLE

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1916 - Appleton's medical dictionary
By Smith Ely Jelliffe

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ATP Binding Cassette, Sub Family B Proteins

  • A subfamily transmembrane the superfamily TRANSPORTERS that closely related in GLYCOPROTEIN. When overexpressed, function as dependent efflux pumps able extrude lipophilic drugs, especially ANTINEOPLASTIC AGENTS, from cells causing resistance (DRUG RESISTANCE, MULTIPLE). Although P-Glycoproteins share functional similarities to MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS they are two distinct subclasses of ATP-BINDING CASSETTE TRANSPORTERS, and have little sequence homology.
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