INAPPROPRIATE GROWTH HORMONE SECRETION SYNDROME (ACROMEGALY)
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Definitions of INAPPROPRIATE GROWTH HORMONE SECRETION SYNDROME (ACROMEGALY)
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A disorder caused by excessive secretion of SOMATOTROPIN, characterized by bony enlargement of the face (especially prognathism), hands, feet, head, and thorax. Impaired glucose tolerance; HYPERTENSION; ARTHRITIS; diffuse hyperplasia of soft tissues; CARPAL TUNNEL SYNDROME; visceromegaly; and MUSCULAR WEAKNESS are frequently associated with this condition. The most common etiology is a somatotropin secreting pituitary ADENOMA (see also PITUITARY NEOPLASMS). (From Joynt, Clinical Neurology, 1992, Ch36, pp79-80)
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.
Nearby Words
- inappropriate adh syndrome
- inappropriate adrenocorticotropic hormone secretion
- inappropriate follicle stimulating hormone secretion
- inappropriate fsh secretion syndrome
- inappropriate gh secretion syndrome (acromegaly)
- Inappropriate Growth Hormone Secretion Syndrome (Acromegaly)
- inappropriate lh secretion syndrome
- inappropriate luteinizing hormone secretion
- inappropriate prolactin secretion
- inappropriate prolactin secretion syndrome
- inappropriate secretion prolactin