INADAPTABILITY

\ɪnɐdˌaptəbˈɪlɪti], \ɪnɐdˌaptəbˈɪlɪti], \ɪ_n_ɐ_d_ˌa_p_t_ə_b_ˈɪ_l_ɪ_t_i]\
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1919 - The concise Oxford dictionary of current English
By Sir Augustus Henry

Word of the day

ATP Binding Cassette, Sub Family B Proteins

  • A subfamily transmembrane the superfamily TRANSPORTERS that closely related in GLYCOPROTEIN. When overexpressed, function as dependent efflux pumps able extrude lipophilic drugs, especially ANTINEOPLASTIC AGENTS, from cells causing resistance (DRUG RESISTANCE, MULTIPLE). Although P-Glycoproteins share functional similarities to MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS they are two distinct subclasses of ATP-BINDING CASSETTE TRANSPORTERS, and have little sequence homology.
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