IG VARIABLE REGION
\ˈɪɡ vˈe͡əɹɪəbə͡l ɹˈiːd͡ʒən], \ˈɪɡ vˈeəɹɪəbəl ɹˈiːdʒən], \ˈɪ_ɡ v_ˈeə_ɹ_ɪ__ə_b_əl ɹ_ˈiː_dʒ_ə_n]\
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That region of the immunoglobulin (antibody) molecule that varies in its amino acid sequence and composition, confers the antigenic specificity, and is thought to comprise the binding site for the antigen. It is located at the N-terminus of the Fab fragment of the immunoglobulin. It includes hypervariable regions (COMPLEMENTARITY DETERMINING REGIONS) and framework regions.
By DataStellar Co., Ltd
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