IG CONSTANT REGION
\ˈɪɡ kˈɒnstənt ɹˈiːd͡ʒən], \ˈɪɡ kˈɒnstənt ɹˈiːdʒən], \ˈɪ_ɡ k_ˈɒ_n_s_t_ə_n_t ɹ_ˈiː_dʒ_ə_n]\
Definitions of IG CONSTANT REGION
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That region of the immunoglobulin (antibody) molecule that is invariable in its amino acid sequence within any class of immunoglobulins. It confers the biological specificity to the Ig and is grossly species specific. It comprises the C-terminus half of the light chains and three quarters or more of the heavy chains, all of the Fc fragment, and the C-terminus half of the Fab fragment.
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