IC50
\ˈa͡ɪk fˈɪfti], \ˈaɪk fˈɪfti], \ˈaɪ_k f_ˈɪ_f_t_i]\
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The concentration of a compound needed to reduce population growth of organisms, including eukaryotic cells, by 50% in vitro. Though often expressed to denote in vitro antibacterial activity, it is also used as a benchmark for cytotoxicity to eukaryotic cells in culture.
By DataStellar Co., Ltd
Word of the day
bcr v abl Oncogene
- Retrovirus-associated DNA sequences (abl) originally isolated from Abelson murine leukemia virus (Ab-MuLV). proto-oncogene abl (codes for a protein that member tyrosine kinase family. human c-abl gene is located at 9q34.1 on the long arm of chromosome 9. It activated by translocation to bcr 22 in chronic myelogenous leukemia.