I KAPPA B
\a͡ɪ kˈapə bˈiː], \aɪ kˈapə bˈiː], \aɪ k_ˈa_p_ə b_ˈiː]\
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Family of inhibitory proteins which bind to the rel family of transcription factors and modulate their activity. The transcription factor NF-KAPPA B is generally present in an inactive cytoplasmic form, bound to inhibitory IkB proteins. Cell stimulation causes its dissociation and translocation of active NF-kappa B to the nucleus.
By DataStellar Co., Ltd
Word of the day
Procollagen Proline Dioxygenase
- mixed-function oxygenase that catalyzes hydroxylation prolyl-glycyl-containing-peptide, usually in protocollagen, hydroxyprolylglycyl-peptide. The enzyme utilizes molecular oxygen with a concomitant oxidative decarboxylation of 2-oxoglutarate to succinate. EC 1.14.11.2.