HYPNOTIC TRANCE
\hɪpnˈɒtɪk tɹˈans], \hɪpnˈɒtɪk tɹˈans], \h_ɪ_p_n_ˈɒ_t_ɪ_k t_ɹ_ˈa_n_s]\
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By Princeton University
Word of the day
ATP Binding Cassette, Sub Family B Proteins
- A subfamily transmembrane the superfamily TRANSPORTERS that closely related in GLYCOPROTEIN. When overexpressed, function as dependent efflux pumps able extrude lipophilic drugs, especially ANTINEOPLASTIC AGENTS, from cells causing resistance (DRUG RESISTANCE, MULTIPLE). Although P-Glycoproteins share functional similarities to MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS they are two distinct subclasses of ATP-BINDING CASSETTE TRANSPORTERS, and have little sequence homology.