HYPERVARIABLE REGION
\hˈa͡ɪpəvˌe͡əɹɪəbə͡l ɹˈiːd͡ʒən], \hˈaɪpəvˌeəɹɪəbəl ɹˈiːdʒən], \h_ˈaɪ_p_ə_v_ˌeə_ɹ_ɪ__ə_b_əl ɹ_ˈiː_dʒ_ə_n]\
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Three regions (CDR1; CDR2 and CDR3) of amino acid sequence in the IMMUNOGLOBULIN VARIABLE REGION that are highly divergent. Together the CDRs from the light and heavy immunoglobulin chains form a surface that is complementary to the antigen. These regions are also present in other members of the immunoglobulin superfamily, for example, T-cell receptors (RECEPTORS, ANTIGEN, T-CELL).
By DataStellar Co., Ltd
