HYDROXYMETHYLGLUTARYL COENZYME A INHIBITORS

\hˈa͡ɪdɹəksˌa͡ɪmθɪlɡlˌuːtɑːɹˌɪl kˌə͡ʊˈɛnza͡ɪm ɐ ɪnhˈɪbɪtəz], \hˈa‍ɪdɹəksˌa‍ɪmθɪlɡlˌuːtɑːɹˌɪl kˌə‍ʊˈɛnza‍ɪm ɐ ɪnhˈɪbɪtəz], \h_ˈaɪ_d_ɹ_ə_k_s_ˌaɪ_m_θ_ɪ_l_ɡ_l_ˌuː_t_ɑː_ɹ_ˌɪ_l k_ˌəʊ_ˈɛ_n_z_aɪ_m ɐ ɪ_n_h_ˈɪ_b_ɪ_t_ə_z]\

Definitions of HYDROXYMETHYLGLUTARYL COENZYME A INHIBITORS

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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