HYBRIDIZATION IN SITU, FLUORESCENT
\hˌa͡ɪbɹɪda͡ɪzˈe͡ɪʃən ɪn sˈɪtuː], \hˌaɪbɹɪdaɪzˈeɪʃən ɪn sˈɪtuː], \h_ˌaɪ_b_ɹ_ɪ_d_aɪ_z_ˈeɪ_ʃ_ə_n ɪ_n s_ˈɪ_t_uː]\
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A type of IN SITU HYBRIDIZATION in which target sequences are stained with fluorescent dye so their location and size can be determined using fluorescence microscopy. This staining is sufficiently distinct that the hybridization signal can be seen both in metaphase spreads and in interphase nuclei.
By DataStellar Co., Ltd
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.
Nearby Words
- hybridity
- hybridizable
- hybridization
- hybridization in situ
- hybridization in situ, fluorescence
- Hybridization in Situ, Fluorescent
- hybridizations
- hybridize
- hybridized
- hybridizer
- hybridizing