HUTCHINSON'S CRESCENTIC NOTCH

\hˈʌt͡ʃɪnsənz kɹɛsˈɛntɪk nˈɒt͡ʃ], \hˈʌt‍ʃɪnsənz kɹɛsˈɛntɪk nˈɒt‍ʃ], \h_ˈʌ_tʃ_ɪ_n_s_ə_n_z k_ɹ_ɛ_s_ˈɛ_n_t_ɪ_k n_ˈɒ_tʃ]\

Definitions of HUTCHINSON'S CRESCENTIC NOTCH

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Proto Oncogene Proteins c erbB 2

  • cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.
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