HOSPITALIZATIONS

\hˌɒspɪtəla͡ɪzˈe͡ɪʃənz], \hˌɒspɪtəla‍ɪzˈe‍ɪʃənz], \h_ˌɒ_s_p_ɪ_t_ə_l_aɪ_z_ˈeɪ_ʃ_ə_n_z]\

Definitions of HOSPITALIZATIONS

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2010 - Medical Dictionary Database
By DataStellar Co., Ltd

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ATP Binding Cassette, Sub Family B Proteins

  • A subfamily transmembrane the superfamily TRANSPORTERS that closely related in GLYCOPROTEIN. When overexpressed, function as dependent efflux pumps able extrude lipophilic drugs, especially ANTINEOPLASTIC AGENTS, from cells causing resistance (DRUG RESISTANCE, MULTIPLE). Although P-Glycoproteins share functional similarities to MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS they are two distinct subclasses of ATP-BINDING CASSETTE TRANSPORTERS, and have little sequence homology.
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