HOMOLOGOUS RESTRICTION FACTOR 20
\həmˈɒləɡəs ɹɪstɹˈɪkʃən fˈaktə twˈɛnti], \həmˈɒləɡəs ɹɪstɹˈɪkʃən fˈaktə twˈɛnti], \h_ə_m_ˈɒ_l_ə_ɡ_ə_s ɹ_ɪ_s_t_ɹ_ˈɪ_k_ʃ_ə_n f_ˈa_k_t_ə t_w_ˈɛ_n_t_i]\
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Small glycoproteins found on both hematopoietic and non-hematopoietic cells. CD59 restricts the cytolytic activity of homologous complement by binding to C8 and C9 and blocking the assembly of the membrane attack complex. (From Barclay et al., The Leukocyte Antigen FactsBook, 1993, p234)
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.