HLA ANTIGENS
\ˌe͡ɪt͡ʃˌɛlˈe͡ɪ ˈantɪd͡ʒˌɛnz], \ˌeɪtʃˌɛlˈeɪ ˈantɪdʒˌɛnz], \ˌeɪ_tʃ_ˌɛ_l_ˈeɪ ˈa_n_t_ɪ_dʒ_ˌɛ_n_z]\
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Antigens determined by leukocyte loci found on chromosome 6, the major histocompatibility loci in humans. They are polypeptides or glycoproteins found on most nucleated cells and platelets, determine tissue types for transplantation, and are associated with certain diseases.
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.