HIV 1 ENVELOPE PROTEIN GP120
\ˌe͡ɪt͡ʃˌa͡ɪvˈiː wˈɒn ˈɛnvəlˌə͡ʊp pɹˈə͡ʊtiːn d͡ʒˌiːpˈiː wˈɒnhˈʌndɹədən twˈɛnti], \ˌeɪtʃˌaɪvˈiː wˈɒn ˈɛnvəlˌəʊp pɹˈəʊtiːn dʒˌiːpˈiː wˈɒnhˈʌndɹədən twˈɛnti], \ˌeɪ_tʃ_ˌaɪ_v_ˈiː w_ˈɒ_n ˈɛ_n_v_ə_l_ˌəʊ_p p_ɹ_ˈəʊ_t_iː_n dʒ_ˌiː_p_ˈiː w_ˈɒ_n_h_ˈʌ_n_d_ɹ_ə_d_ə_n t_w_ˈɛ_n_t_i]\
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External envelope protein of the human immunodeficiency virus which is encoded by the HIV env gene. It has a molecular weight of 120 kD and contains numerous glycosylation sites. Gp120 binds to cells expressing CD4 cell-surface antigens, most notably T4-lymphocytes and monocytes/macrophages. Gp120 has been shown to interfere with the normal function of CD4 and is at least partly responsible for the cytopathic effect of HIV.
By DataStellar Co., Ltd
Word of the day
tinctura quininae ammoniata
- A preparation made by dissolving quinin sulphate in alcohol [Br. Ph.].