HIV 1 ASSOCIATED CNS VASCULITIS
\ˌe͡ɪt͡ʃˌa͡ɪvˈiː wˈɒn ɐsˈə͡ʊsɪˌe͡ɪtɪd sˌiːˌɛnˈɛs vˌaskjʊlˈa͡ɪtɪs], \ˌeɪtʃˌaɪvˈiː wˈɒn ɐsˈəʊsɪˌeɪtɪd sˌiːˌɛnˈɛs vˌaskjʊlˈaɪtɪs], \ˌeɪ_tʃ_ˌaɪ_v_ˈiː w_ˈɒ_n ɐ_s_ˈəʊ_s_ɪ__ˌeɪ_t_ɪ_d s_ˌiː__ˌɛ_n_ˈɛ_s v_ˌa_s_k_j_ʊ_l_ˈaɪ_t_ɪ_s]\
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Inflammation of blood vessels of the CENTRAL NERVOUS SYSTEM that occurs in association with the ACQUIRED IMMUNODEFICIENCY SYNDROME. In children, this condition may be associated with INTRACRANIAL ANEURYSM formation. Cerebral vasculitis in this setting is frequently associated with AIDS-RELATED OPPORTUNISTIC INFECTIONS including varicella, CMV, fungal, tuberculosis, and syphilis. (From Neurol Clin 1997 Nov;15 (4):927-44; Neurology 1998 Aug;51 (2):560-5)
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.