HETERODUPLEX DNA
\hˈɛtɹə͡ʊdjˌuːplɛks dˌiːˌɛnˈe͡ɪ], \hˈɛtɹəʊdjˌuːplɛks dˌiːˌɛnˈeɪ], \h_ˈɛ_t_ɹ_əʊ_d_j_ˌuː_p_l_ɛ_k_s d_ˌiː__ˌɛ_n_ˈeɪ]\
Sort: Oldest first
-
Double-stranded nucleic acid molecules (DNA-DNA or DNA-RNA) which contain regions of nucleotide mismatches (non-complementary). In vivo, these heteroduplexes can result from mutation or genetic recombination; in vitro, they are formed by nucleic acid hybridization. Electron microscopic analysis of the resulting heteroduplexes facilitates the mapping of regions of base sequence homology of nucleic acids.
By DataStellar Co., Ltd
Word of the day
Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.