HB A1A 1
\ˌe͡ɪt͡ʃbˈiː ˌe͡ɪ wˈɒn ˈe͡ɪ wˈɒn], \ˌeɪtʃbˈiː ˌeɪ wˈɒn ˈeɪ wˈɒn], \ˌeɪ_tʃ_b_ˈiː_ ˌeɪ w_ˈɒ_n ˈeɪ w_ˈɒ_n]\
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Minor hemoglobin components of human erythrocytes designated A1a, A1b, and A1c. Hemoglobin A1c is most important since its sugar moiety is glucose covalently bound to the terminal amino acid of the beta chain. Since normal glycohemoglobin concentrations exclude marked blood glucose fluctuations over the preceding three to four weeks, the concentration of glycosylated hemoglobin A is a more reliable index of the blood sugar average over a long period of time.
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.