HARVEY SARCOMA VIRUS

\hˈɑːvi sɑːkˈə͡ʊmə vˈa͡ɪɹəs], \hˈɑːvi sɑːkˈə‍ʊmə vˈa‍ɪɹəs], \h_ˈɑː_v_i s_ɑː_k_ˈəʊ_m_ə v_ˈaɪ_ɹ_ə_s]\

Definitions of HARVEY SARCOMA VIRUS

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2010 - Medical Dictionary Database
By DataStellar Co., Ltd

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ATP Binding Cassette, Sub Family B Proteins

  • A subfamily transmembrane the superfamily TRANSPORTERS that closely related in GLYCOPROTEIN. When overexpressed, function as dependent efflux pumps able extrude lipophilic drugs, especially ANTINEOPLASTIC AGENTS, from cells causing resistance (DRUG RESISTANCE, MULTIPLE). Although P-Glycoproteins share functional similarities to MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS they are two distinct subclasses of ATP-BINDING CASSETTE TRANSPORTERS, and have little sequence homology.
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