HARTE, FRANCIS BRET
\hˈɑːt], \hˈɑːt], \h_ˈɑː_t]\
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Born in New York in 1839, was associated with the San Francisco Golden Era in 1857, edited for a short time the Californian, and in 1868 established the Overland Monthly. He has mostly written sketches of American frontier life. From 1880 to 1885 he was U.S. Consul at Glasgow.
By John Franklin Jameson
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.