HAMILTON'S METHOD

\hˈamə͡ltənz mˈɛθəd], \hˈamə‍ltənz mˈɛθəd], \h_ˈa_m_əl_t_ə_n_z m_ˈɛ_θ_ə_d]\

Definitions of HAMILTON'S METHOD

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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