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Definitions of H 16868

  1. A highly effective inhibitor of gastric acid secretion used in the therapy of gastric ulcers and Zollinger- Ellison syndrome. The drug inhibits the H(+)- K(+)- ATPase ( H(+)- K(+)- EXCHANGING ATPASE) in a pH- dependent manner. This ATPase is considered the proton pump in the secretory membrane of the parietal cell.
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