GLYCOPROTEIN GP68
\ɡlˈa͡ɪkəpɹˌə͡ʊtiːn d͡ʒˌiːpˈiː sˈɪkstiˈe͡ɪt], \ɡlˈaɪkəpɹˌəʊtiːn dʒˌiːpˈiː sˈɪkstiˈeɪt], \ɡ_l_ˈaɪ_k_ə_p_ɹ_ˌəʊ_t_iː_n dʒ_ˌiː_p_ˈiː s_ˈɪ_k_s_t_i__ˈeɪ_t]\
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Glycoprotein found in alpha (1)-globulin region in human serum. It inhibits chymotrypsin-like proteinases in vivo and has cytotoxic killer-cell activity in vitro. The protein also has a role as an acute-phase protein and is active in the control of immunologic and inflammatory processes, and as a tumor marker. It is a member of the serpin superfamily.
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.