GLYCOPROTEIN IB IX COMPLEX
\ɡlˈa͡ɪkəpɹˌə͡ʊtiːn ˈa͡ɪb ɹˌə͡ʊmən nˈa͡ɪn kˈɒmplɛks], \ɡlˈaɪkəpɹˌəʊtiːn ˈaɪb ɹˌəʊmən nˈaɪn kˈɒmplɛks], \ɡ_l_ˈaɪ_k_ə_p_ɹ_ˌəʊ_t_iː_n ˈaɪ_b ɹ_ˌəʊ_m_ə_n_ n_ˈaɪ_n k_ˈɒ_m_p_l_ɛ_k_s]\
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Platelet membrane glycoprotein complex essential for normal platelet adhesion and clot formation at sites of vascular injury. It is composed of three polypeptides, GPIb alpha, GPIb beta, and GPIX. Glycoprotein Ib functions as a receptor for von Willebrand factor and for thrombin. Congenital deficiency of the GPIb-IX complex results in Bernard-Soulier syndrome. The platelet glycoprotein GPV associates with GPIb-IX and is also absent in Bernard-Soulier syndrome.
By DataStellar Co., Ltd
Word of the day
hydromorphic
- [Greek] Structurally adapted to an aquatic environment, as organs of water plants.