GLIOBLASTOMA WITH SARCOMATOUS COMPONENT
\ɡlɪˌɒblastˈə͡ʊmə wɪð sˌɑːkəmˈatəs kəmpˈə͡ʊnənt], \ɡlɪˌɒblastˈəʊmə wɪð sˌɑːkəmˈatəs kəmpˈəʊnənt], \ɡ_l_ɪ__ˌɒ_b_l_a_s_t_ˈəʊ_m_ə w_ɪ_ð s_ˌɑː_k_ə_m_ˈa_t_ə_s k_ə_m_p_ˈəʊ_n_ə_n_t]\
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Rare mixed tumors of the brain and rarely the spinal cord which contain malignant neuroectodermal (glial) and mesenchymal components, including spindle-shaped fibrosarcoma cells. These tumors are highly aggressive and present primarily in adults as rapidly expanding mass lesions. They may arise in tissue that has been previously irradiated. (From Br J Neurosurg 1995 Apr;9 (2):171-8)
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.
Nearby Words
- glinting
- glio'sis
- gliobacteria
- glioblastoma
- glioblastoma multiforme
- Glioblastoma with Sarcomatous Component
- glioblastomas
- gliocladium
- gliococcus
- gliococens
- glioma