GENERALIZED HEADACHE
\d͡ʒˈɛnəɹə͡lˌa͡ɪzd hˈɛde͡ɪk], \dʒˈɛnəɹəlˌaɪzd hˈɛdeɪk], \dʒ_ˈɛ_n_ə_ɹ_əl_ˌaɪ_z_d h_ˈɛ_d_eɪ_k]\
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Pain in the cranial region that may occur as an isolated and benign symptom or as a manifestation of a wide variety of conditions including SUBARACHNOID HEMORRHAGE; CRANIOCEREBRAL TRAUMA; CENTRAL NERVOUS SYSTEM INFECTIONS; INTRACRANIAL HYPERTENSION; and other disorders. In general, recurrent headaches that are not associated with a primary disease process are referred to as HEADACHE DISORDERS (e.g., MIGRAINE).
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.