GENERAL AGREEMENT ON TARIFFS AND TRADE (GATT)

\d͡ʒˈɛnəɹə͡l ɐɡɹˈiːmənt ˌɒn tˈaɹɪfs and tɹˈe͡ɪd ɡˈat], \d‍ʒˈɛnəɹə‍l ɐɡɹˈiːmənt ˌɒn tˈaɹɪfs and tɹˈe‍ɪd ɡˈat], \dʒ_ˈɛ_n_ə_ɹ_əl ɐ_ɡ_ɹ_ˈiː_m_ə_n_t ˌɒ_n t_ˈa_ɹ_ɪ_f_s__ a_n_d t_ɹ_ˈeɪ_d__ ɡ_ˈa_t]\

Definitions of GENERAL AGREEMENT ON TARIFFS AND TRADE (GATT)

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ATP Binding Cassette, Sub Family B Proteins

  • A subfamily transmembrane the superfamily TRANSPORTERS that closely related in GLYCOPROTEIN. When overexpressed, function as dependent efflux pumps able extrude lipophilic drugs, especially ANTINEOPLASTIC AGENTS, from cells causing resistance (DRUG RESISTANCE, MULTIPLE). Although P-Glycoproteins share functional similarities to MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS they are two distinct subclasses of ATP-BINDING CASSETTE TRANSPORTERS, and have little sequence homology.
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