GENERAL AGGREGATE LIMIT

\d͡ʒˈɛnəɹə͡l ˈaɡɹɪɡˌe͡ɪt lˈɪmɪt], \d‍ʒˈɛnəɹə‍l ˈaɡɹɪɡˌe‍ɪt lˈɪmɪt], \dʒ_ˈɛ_n_ə_ɹ_əl ˈa_ɡ_ɹ_ɪ_ɡ_ˌeɪ_t l_ˈɪ_m_ɪ_t]\

Definitions of GENERAL AGGREGATE LIMIT

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1910 - Black's Law Dictionary (2nd edition)
By Henry Campbell Black

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ATP Binding Cassette, Sub Family B Proteins

  • A subfamily transmembrane the superfamily TRANSPORTERS that closely related in GLYCOPROTEIN. When overexpressed, function as dependent efflux pumps able extrude lipophilic drugs, especially ANTINEOPLASTIC AGENTS, from cells causing resistance (DRUG RESISTANCE, MULTIPLE). Although P-Glycoproteins share functional similarities to MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS they are two distinct subclasses of ATP-BINDING CASSETTE TRANSPORTERS, and have little sequence homology.
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