GEL ELECTROPHORESIS, SINGLE CELL
\d͡ʒˈɛl ɪlˌɛktɹə͡ʊfɔːɹˈiːsɪs], \dʒˈɛl ɪlˌɛktɹəʊfɔːɹˈiːsɪs], \dʒ_ˈɛ_l ɪ_l_ˌɛ_k_t_ɹ_əʊ_f_ɔː_ɹ_ˈiː_s_ɪ_s]\
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A genotoxicological technique for measuring DNA damage in an individual cell using single-cell gel electrophoresis. Cell DNA fragments assume a "comet with tail" formation on electrophoresis and are detected with an image analysis system. Alkaline assay conditions facilitate sensitive detection of single-strand damage.
By DataStellar Co., Ltd
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.