GANGLIOSIDE GM3
\ɡˈaŋɡlɪˌɒsa͡ɪd d͡ʒˌiːˈɛm θɹˈiː], \ɡˈaŋɡlɪˌɒsaɪd dʒˌiːˈɛm θɹˈiː], \ɡ_ˈa_ŋ_ɡ_l_ɪ__ˌɒ_s_aɪ_d dʒ_ˌiː__ˈɛ_m θ_ɹ_ˈiː]\
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A ganglioside present in abnormally large amounts in the brain and liver due to a deficient biosynthetic enzyme, G (M3):UDP-N-acetylgalactosaminyltransferase. Deficiency of this enzyme prevents the formation of G (M2) ganglioside from G (M3) ganglioside and is the cause of an anabolic sphingolipidosis.
By DataStellar Co., Ltd
