GAMSTORP WOHLFART SYNDROME
\ɡˈamstɔːp wˈə͡ʊlfɑːt sˈɪndɹə͡ʊm], \ɡˈamstɔːp wˈəʊlfɑːt sˈɪndɹəʊm], \ɡ_ˈa_m_s_t_ɔː_p w_ˈəʊ_l_f_ɑː_t s_ˈɪ_n_d_ɹ_əʊ_m]\
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A rare neuromuscular disorder with onset usually in late childhood or early adulthood, characterized by intermittent or continuous widespread involuntary muscle contractions; FASCICULATION; hyporeflexia; MUSCLE CRAMP; MUSCLE WEAKNESS; HYPERHIDROSIS; TACHYCARDIA; and MYOKYMIA. Involvement of pharyngeal or laryngeal muscles may interfere with speech and breathing. The continuous motor activity persists during sleep and general anesthesia (distinguishing this condition from STIFF-PERSON SYNDROME). Familial and acquired (primarily autoimmune) forms have been reported. (From Ann NY Acad Sci 1998 May 13;841:482-496; Adams et al., Principles of Neurology, 6th ed, p1491)
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Word of the day
hydromorphic
- [Greek] Structurally adapted to an aquatic environment, as organs of water plants.
Nearby Words
- gamotropism
- gamow
- gamp
- gamphe
- gamphele
- Gamstorp Wohlfart Syndrome
- gamstorp wohlfart syndromes
- gamul
- gamulin rh
- gamut
- gamy