GADSDEN, JAMES
\ɡˈadsdən], \ɡˈadsdən], \ɡ_ˈa_d_s_d_ə_n]\
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(1788-1858), served in the War of 1812, was aide-de-camp to General Jackson in the subjugation of the Seminole Indians, and constructed works for the defense of the Gulf. He was appointed Minister to Mexico in 1853 by President Pierce, and negotiated the Gadsden Treaty, which secured the purchase of the southern portion of Arizona and New Mexico.
By John Franklin Jameson
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.