FORMATIO RETIENLARIS
\fɔːmˈe͡ɪʃɪˌə͡ʊ ɹˈɛʃənlˌɑːɹɪs], \fɔːmˈeɪʃɪˌəʊ ɹˈɛʃənlˌɑːɹɪs], \f_ɔː_m_ˈeɪ_ʃ_ɪ__ˌəʊ ɹ_ˈɛ_ʃ_ə_n_l_ˌɑː_ɹ_ɪ_s]\
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.