FOLATE POLYGLUTAMATES
\fˈɒle͡ɪt pˌɒlɪɡlˈuːtɐmˌe͡ɪts], \fˈɒleɪt pˌɒlɪɡlˈuːtɐmˌeɪts], \f_ˈɒ_l_eɪ_t p_ˌɒ_l_ɪ_ɡ_l_ˈuː_t_ɐ_m_ˌeɪ_t_s]\
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Derivatives of folic acid (pteroylglutamic acid). In gamma-glutamyl linkage they are found in many tissues. They are converted to folic acid by the action of pteroylpolyglutamate hydrolase or synthesized from folic acid by the action of folate polyglutamate synthetase. Synthetic pteroylpolyglutamic acids, which are in alpha-glutamyl linkage, are active in bacterial growth assays.
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Word of the day
Dopamine Acetyltransferase
- An enzyme that catalyzes the of groups from acetyl-CoA to arylamines. They have wide specificity for aromatic amines, particularly serotonin, and can also catalyze acetyl transfer between arylamines without CoA. EC 2.3.1.5.