\fˈə͡ʊkə͡l ɐdhˈiːʒən], \fˈəʊkəl ɐdhˈiːʒən], \f_ˈəʊ_k_əl ɐ_d_h_ˈiː_ʒ_ə_n]\
Definitions of FOCAL ADHESION
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An anchoring junction of the cell to a non-cellular substrate. It is composed of a specialized area of the plasma membrane where bundles of MICROFILAMENTS terminate and attach to the transmembrane linkers, INTEGRINS, which in turn attach through their extracellular domains to EXTRACELLULAR MATRIX PROTEINS.
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