FOCAL ADHESION
\fˈə͡ʊkə͡l ɐdhˈiːʒən], \fˈəʊkəl ɐdhˈiːʒən], \f_ˈəʊ_k_əl ɐ_d_h_ˈiː_ʒ_ə_n]\
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An anchoring junction of the cell to a non-cellular substrate. It is composed of a specialized area of the plasma membrane where bundles of MICROFILAMENTS terminate and attach to the transmembrane linkers, INTEGRINS, which in turn attach through their extracellular domains to EXTRACELLULAR MATRIX PROTEINS.
By DataStellar Co., Ltd
