FMS ONCOGENE PROTEIN GP140
\ˌɛfˌɛmˈɛs ˈɒnkə͡ʊd͡ʒˌiːn pɹˈə͡ʊtiːn d͡ʒˌiːpˈiː wˈɒnhˈʌndɹədən fˈɔːti], \ˌɛfˌɛmˈɛs ˈɒnkəʊdʒˌiːn pɹˈəʊtiːn dʒˌiːpˈiː wˈɒnhˈʌndɹədən fˈɔːti], \ˌɛ_f_ˌɛ_m_ˈɛ_s ˈɒ_n_k_əʊ_dʒ_ˌiː_n p_ɹ_ˈəʊ_t_iː_n dʒ_ˌiː_p_ˈiː w_ˈɒ_n_h_ˈʌ_n_d_ɹ_ə_d_ə_n f_ˈɔː_t_i]\
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Transforming glycoprotein coded by the fms oncogene from the Susan McDonough strain of feline sarcoma virus (SM-FeSV). The oncogene protein v-fms lacks sequences, which, in the highly homologous proto-oncogene protein c-fms (CSF-1 receptor), normally serve to regulate its tyrosine kinase activity. The missing sequences in v-fms mimic the effect of ligand and lead to constitutive cell growth. The protein gp120 (v-fms) is post-translationally modified to generate gp140 (v-fms).
By DataStellar Co., Ltd
Word of the day
tinctura quininae ammoniata
- A preparation made by dissolving quinin sulphate in alcohol [Br. Ph.].
Nearby Words
- fms gene
- fms genes
- fms oncogene product gp120
- fms oncogene product gp140
- fms oncogene protein gp120
- fms Oncogene Protein gp140
- fms proto oncogene protein
- fnese
- fnma
- fo
- fo 1561