FILIPIN II
\fˈɪlɪpˌɪn ɹˌə͡ʊmən tˈuː], \fˈɪlɪpˌɪn ɹˌəʊmən tˈuː], \f_ˈɪ_l_ɪ_p_ˌɪ_n ɹ_ˌəʊ_m_ə_n_ t_ˈuː]\
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A complex of polyene antibiotics obtained from Streptomyces filipinensis. Filipin III alters membrane function by interfering with membrane sterols, inhibits mitochondrial respiration, and is proposed as an antifungal agent. Filipins I, II, and IV are less important.
By DataStellar Co., Ltd
Word of the day
Procollagen Proline Dioxygenase
- mixed-function oxygenase that catalyzes hydroxylation prolyl-glycyl-containing-peptide, usually in protocollagen, hydroxyprolylglycyl-peptide. The enzyme utilizes molecular oxygen with a concomitant oxidative decarboxylation of 2-oxoglutarate to succinate. EC 1.14.11.2.