FENCLONINE HYDROCHLORIDE

\fˈɛŋklənˌa͡ɪn hˈa͡ɪdɹəklˌɔːɹa͡ɪd], \fˈɛŋklənˌa‍ɪn hˈa‍ɪdɹəklˌɔːɹa‍ɪd], \f_ˈɛ_ŋ_k_l_ə_n_ˌaɪ_n h_ˈaɪ_d_ɹ_ə_k_l_ˌɔː_ɹ_aɪ_d]\

Definitions of FENCLONINE HYDROCHLORIDE

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2010 - Medical Dictionary Database
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ATP Binding Cassette, Sub Family B Proteins

  • A subfamily transmembrane the superfamily TRANSPORTERS that closely related in GLYCOPROTEIN. When overexpressed, function as dependent efflux pumps able extrude lipophilic drugs, especially ANTINEOPLASTIC AGENTS, from cells causing resistance (DRUG RESISTANCE, MULTIPLE). Although P-Glycoproteins share functional similarities to MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS they are two distinct subclasses of ATP-BINDING CASSETTE TRANSPORTERS, and have little sequence homology.
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