FENCLONINE (L) ISOMER

\fˈɛŋklənˌa͡ɪn ˈɛl ˈa͡ɪsəmə], \fˈɛŋklənˌa‍ɪn ˈɛl ˈa‍ɪsəmə], \f_ˈɛ_ŋ_k_l_ə_n_ˌaɪ_n__ ˈɛ_l__ ˈaɪ_s_ə_m_ə]\

Definitions of FENCLONINE (L) ISOMER

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2010 - Medical Dictionary Database
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ATP Binding Cassette, Sub Family B Proteins

  • A subfamily transmembrane the superfamily TRANSPORTERS that closely related in GLYCOPROTEIN. When overexpressed, function as dependent efflux pumps able extrude lipophilic drugs, especially ANTINEOPLASTIC AGENTS, from cells causing resistance (DRUG RESISTANCE, MULTIPLE). Although P-Glycoproteins share functional similarities to MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS they are two distinct subclasses of ATP-BINDING CASSETTE TRANSPORTERS, and have little sequence homology.
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