FEEDBACK INHIBITION, BIOCHEMICAL
\fˈiːdbak ɪnhɪbˈɪʃən], \fˈiːdbak ɪnhɪbˈɪʃən], \f_ˈiː_d_b_a_k ɪ_n_h_ɪ_b_ˈɪ_ʃ_ə_n]\
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A mechanism of communication among life processes to coordinate development, reproduction, and homeostasis. In humans, feedback loops are especially important for communication between organs that are spatially separated. Virtually all hormones from the nervous and endocrine systems are under feedback control: by peripheral hormones, cations, metabolites, osmolarity or extracellular fluid volume.
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.