FAMILIAL RETINOBLASTOMAS
\famˈɪlɪəl ɹˌɛtɪnˌə͡ʊblastˈə͡ʊməz], \famˈɪlɪəl ɹˌɛtɪnˌəʊblastˈəʊməz], \f_a_m_ˈɪ_l_ɪ__ə_l ɹ_ˌɛ_t_ɪ_n_ˌəʊ_b_l_a_s_t_ˈəʊ_m_ə_z]\
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A malignant tumor arising from the nuclear layer of the retina that is the most common primary tumor of the eye in children. The tumor tends to occur in early childhood or infancy and may be present at birth. The majority are sporadic, but the condition may be transmitted as an autosomal dominant trait. Histologic features include dense cellularity, small round polygonal cells, and areas of calcification and necrosis. An abnormal pupil reflex (leukokoria); NYSTAGMUS; STRABISMUS; and visual loss represent common clinical characteristics of this condition. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, p2104)
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tinctura quininae ammoniata
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Nearby Words
- familial polyposis coli
- familial polyposis syndrome
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- familial progressive myoclonic epilepsy
- familial retinoblastoma
- Familial Retinoblastomas
- familial spinocerebellar degeneration
- familial spinocerebellar degenerations
- familial tonic clonic epilepsies
- familial tonic clonic epilepsy
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