FACTOR VIII HEAVY CHAIN
\fˈaktə ɹˌə͡ʊmən ˈe͡ɪt hˈɛvi t͡ʃˈe͡ɪn], \fˈaktə ɹˌəʊmən ˈeɪt hˈɛvi tʃˈeɪn], \f_ˈa_k_t_ə ɹ_ˌəʊ_m_ə_n_ ˈeɪ_t h_ˈɛ_v_i tʃ_ˈeɪ_n]\
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Blood-coagulation factor VIII. Antihemophilic factor that is part of the factor VIII/von Willebrand factor complex. Factor VIII is produced in the liver and acts in the intrinsic pathway of blood coagulation. It serves as a cofactor in factor X activation and this action is markedly enhanced by small amounts of thrombin.
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