\fˈe͡ɪsɪˌə͡ʊ ˈʌt dˈɛs], \fˈe‍ɪsɪˌə‍ʊ ˈʌt dˈɛs], \f_ˈeɪ_s_ɪ__ˌəʊ ˈʌ_t d_ˈɛ_s]\

Definitions of FACIO UT DES

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1856 - A Law Dictionary
By John Bouvier

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ATP Binding Cassette, Sub Family B Proteins

  • A subfamily transmembrane the superfamily TRANSPORTERS that closely related in GLYCOPROTEIN. When overexpressed, function as dependent efflux pumps able extrude lipophilic drugs, especially ANTINEOPLASTIC AGENTS, from cells causing resistance (DRUG RESISTANCE, MULTIPLE). Although P-Glycoproteins share functional similarities to MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS they are two distinct subclasses of ATP-BINDING CASSETTE TRANSPORTERS, and have little sequence homology.
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