FACINUS PULCHERRIMUM

\fˈasɪnəs pˈʌlt͡ʃɪɹˌɪməm], \fˈasɪnəs pˈʌlt‍ʃɪɹˌɪməm], \f_ˈa_s_ɪ_n_ə_s p_ˈʌ_l_tʃ_ɪ_ɹ_ˌɪ_m_ə_m]\

Definitions of FACINUS PULCHERRIMUM

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1895 - Glossary of terms and phrases
By Henry Percy Smith

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ATP Binding Cassette, Sub Family B Proteins

  • A subfamily transmembrane the superfamily TRANSPORTERS that closely related in GLYCOPROTEIN. When overexpressed, function as dependent efflux pumps able extrude lipophilic drugs, especially ANTINEOPLASTIC AGENTS, from cells causing resistance (DRUG RESISTANCE, MULTIPLE). Although P-Glycoproteins share functional similarities to MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS they are two distinct subclasses of ATP-BINDING CASSETTE TRANSPORTERS, and have little sequence homology.
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