EXTRAMURAL
\ˈɛkstɹəmjˌʊɹə͡l], \ˈɛkstɹəmjˌʊɹəl], \ˈɛ_k_s_t_ɹ_ə_m_j_ˌʊ_ɹ_əl]\
Word of the day
Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.