EXOPROTEASES
\ɛɡzˈɒpɹə͡ʊtˌe͡ɪsɪz], \ɛɡzˈɒpɹəʊtˌeɪsɪz], \ɛ_ɡ_z_ˈɒ_p_ɹ_əʊ_t_ˌeɪ_s_ɪ_z]\
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A sub-subclass of PEPTIDE HYDROLASES that act only near the ends of polypeptide chains. Exopeptidases are further divided into AMINOPEPTIDASES; EC 3.4.11; DIPEPTIDASES; EC 3.4.13; DIPEPTIDYL PEPTIDASES & tripeptidyl peptidases, EC 3.4.14; peptidyl-dipeptidases, EC 3.4.15; CARBOXYPEPTIDASES; EC 3.4.16 - EC 3.4.18, and omega peptidases, EC 3.4.19. EC 3.4.-.
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.